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Rare disorder: Kolkata woman discovers she is suffering from testicular cancer

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Doctors at Netaji Subhas Chandra Bose Cancer Hospital where the woman went for a checkup found out that she was diagnosed with Androgen Insensitivity Syndrome' -- a condition in which a person is born genetically male, but has all physical traits of a woman.

For thirty years she led a normal life with no complications, until recently, when doctors, while treating her for abdominal pain, discovered that she was a ‘man’ suffering from testicular cancer.

Surprisingly, her 28-year-old sister, who underwent necessary tests following the revelation, was also diagnosed with ‘Androgen Insensitivity Syndrome’ — a condition in which a person is born genetically male, but has all physical traits of a woman.
The 30-year-old Birbhum resident, married for the last nine years, had visited city-based Netaji Subhas Chandra Bose Cancer Hospital with severe pain in lower abdomen a couple of months ago, following which clinical oncologist Dr Anupam Dutta and surgical oncologist Dr Soumen Das conducted her medical tests, and found out her “true identity”.

“From her appearance, she is a woman. Starting from her voice, developed breasts, normal external genitalia, everything is that of a woman. However, uterus and ovaries have been absent since birth. She has also never experienced menstruation,” Dr Dutta told PTI. It’s a very rare condition, and can be found one in every 22,000 people, he said.
After test reports suggested that the person has a “blind vagina”, doctors decided to conduct Karyotyping test, which revealed that her chromosome complement was ‘XY’ and not ‘XX’, as found in a woman.

“We conducted clinical examinations, after she complained of abdominal pain, and found out she has testicles inside her body. A biopsy was conducted, following which she was diagnosed with testicular cancer, also called seminoma, Dr Dutta explained.
Currently, she is undergoing chemotheraphy and her health condition is stable.

“As her testicles remained undeveloped inside the body, there was no secretion of testosterone. Her female hormones, on the other hand, gave her the appearance of a woman,” Dr Dutta stated.

Asked about her reaction to the revelation, he said, “The person has grown up to be a woman. She is married to man for almost a decade. Currently, we are counselling the patient and her husband, advising them to continue living life as they have been.”
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